Which was the first u.s. aircraft carrier to deploy with a mixed-gender crew and an air wing that included more than 400 females?

It is the USS Dwight D. Eisenhower.
An aircraft carrier is basically a large barge or a large flat ship that can hold many different planes, and is long enough for a plane to take off and land on. These large aircraft carriers are usually located in the middle of the ocean, in a location where an airport or landing location on land is not accessible. USS Dwight D. Eisenhower is a nuclear powered aircraft carrier that is currently in service with the United States Navy.